Guideline recommendations (off-label): IV: Note:
For most surgical procedures, joint clinical practice guidelines from the American Society of Health-System Pharmacists, Infectious Diseases Society of America, Surgical Infection Society, and Society for Healthcare Epidemiology of America (ASHP/IDSA/SIS/SHEA)
recommend a dose of 2 g within 60 minutes prior to surgical incision (for nonobese patients weighing <120 kg). Only GI susrgery(+ metronidazole)
+-Cefazolin doses may be repeated intraoperatively in 4 hours if procedure is lengthy or if there is excessive blood loss (Bratzler 2013).
For clean and clean-contaminated procedures, continued prophylactic antibiotics beyond surgical incision closure is not recommended, even in the presence of a drain (CDC [Berríos-Torres 2017]).
PREPROCEDURAL ANTIBIOTICS ONCE!! IS GOOD ENOUGH.
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