[CK] PVCs

https://www.uptodate.com/contents/ventricular-premature-beats?search=frequent%20pvc&sectionRank=1&usage_type=default&anchor=H15572590&source=machineLearning&selectedTitle=1~150&display_rank=1#H15572590

 no clear evidence that VPB suppression with beta blockers or antiarrhythmic drugs improves overall survival in patients who have no symptoms and have not had a major arrhythmic event. Thus, the only indications for the use of beta blockers or antiarrhythmic drugs for VPB suppression are for symptomatic patients or for patients with cardiomyopathy felt to be possibly related to frequent VPBs. Before embarking on drug therapy, however, abstinence should first be advised to an individual with exposure to known stimulants, although this strategy has not been a consistently effective intervention [39]. If VPBs and symptoms persist following abstinence, in the case of absent underlying structural heart disease, offering reassurance to the individual regarding the benign nature of ventricular ectopy may suffice; if not, the next step may be treatment with a beta-blocker and/or a calcium channel blocker. The use of membrane active antiarrhythmic therapy and catheter ablation is reserved for patients who do not respond to treatment with beta blockers or calcium channel blockers, and/or are intolerant or prefer not to take these medications.