2019년 1월 9일 수요일

[CK] OHT infection workup and treatment


Fevers and GPC chains bacteremia. Source to be indentified, but worried this is  from biliary tract. Liver US unremarkable. UA  is bening desite mentioning urinary frequency. He last performed CIC a week ago. REnal US unremarkable.
Dental work 3 weeks ago, risk for infectious endocarditis as well.
Feeling bette r on abx.

Rec:
1. Cont meropene  IV while GPCs are identified- susceptiblities released
2.  Cont Vanc  IV  while GPCs identified.
3. If remains febrile or having more positive cultures, switch to  Dapto IV to cover VRE. Hold off for now.
4. If bili  is going up, consider  repepeat MRCP and involve GI.
5. Obtain CMV PCR  in blood.
6. OBtain blood cultures follow up.
7. Cont monitoring CBC, CMP for antimicrobial toxicity.

IVF!

PAN CULTURE + GI viral + CMV/EBV PCR.
CMV/EBV IgG/IgM/DNA quantity.  + IgG level( for IVIG infusion ! )
Fungitell(Candida, Aspergillus); Platelia(Aspergillus Ag)


* Strep for sore throat.
* BK = KIDNEY Transplant.
* Legionella urine Ag. = URINE/ABDOMEN
*  respiratory/GI direct pathogen test.   = RESP

IV VANC+ZOSYN or MEROPENEM
(Dapto? for VRE but not initial)
Bil = USG + MRCP

low threshold to obtain CT (for OHT, LVAD !!!! = more likely to get!)

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